| 產品編號 |
bs-42483P |
| 英文名稱 |
Recombinant human PTAFR protein, N-GST&C-His
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| 中文名稱 |
重組人血小板活化因子受體蛋白 |
| 別 名 |
Platelet-activating factor receptor; PAF receptor; Ptafr; OTTHUMP00000004041; OTTMUSP00000010350; PAF R; PAF-R; PAFR; Platelet activating factor receptor; Platelet-activating factor receptor; PTAFR; PTAFR_HUMAN; RP23-470B20.1. |
| 理論分子量 |
39.1kDa |
| 性 狀 |
Liquid |
| 濃 度 |
>0.5mg/ml |
| 緩 沖 液 |
20mM Tris-HCL (pH=8.0) with 8M Urea |
| 保存條件 |
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 產品介紹 |
The PAF receptor binds platelet-activating factor (PAF) and is thought to mediate its action via a G protein that activates a phosphatidylinositol-calcium second messenger system. PAF is a chemotactic phospholipid mediator that possesses potent inflammatory, smooth-muscle contractile and hypotensive activity. It has been implicated as a mediator in diverse pathologic processes, such as allergy, asthma, septic shock, arterial thrombosis, and inflammatory processes.
The PAF receptor is induced by granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-5 and n-butyrate. A diverse range of compounds act as PAF receptor antagonists; these may be useful pharmacologically.
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