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Recombinant human Cystatin-C protein, His (bs-41175P)  
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產品編號 bs-41175P
英文名稱 Recombinant human Cystatin-C protein, His
中文名稱 重組人胱抑素C蛋白
別    名 Cystatin 3; Cystatin-3; CST 3;CST3; CST-3; Cystatin C; AD 8; AD8; Amyloid angiopathy and cerebral hemorrhage; Cst 3; Cst3; CST3 protein; Cystatin 3; Cystatin3; CystatinC; Gamma trace; HCCAA; Neuroendocrine basic polypeptide; Post gamma globulin; ARMD11; MGC117328; CYSC. ;Recombinant human Cystatin-C protein, His  
Specific References  (1)     |     bs-41175P has been referenced in 1 publications.
[IF=5.304] Zhi Luo. et al. Novel electrochemiluminescence resonance energy transfer platform involving PTCA@Fe(III)-MIL-88B-NH2@Au as a double-amplified emitter for the detection of cystatin C. MICROCHEM J. 2023 Aug;191:108883  
理論分子量 15kDa
檢測分子量 15
性    狀 Lyophilized or Liquid
物    種 Human
序    列 27-146/146
純    度 >95% as determined by SDS-PAGE
純化方法 AC
內毒素 Not analyzed
表達系統 E.coli
活性 Not tested
標簽 His
緩 沖 液 20mM Tris-HCl (pH8.0) with 300mM NaCl and 500mM Imidazole.
保存條件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin, or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

SWISS:
P01034

Gene ID:
1471

產品圖片
Recombinant human Cystatin-C in SDS-PAGE
The purity of the protein is greater than 83% as determined by reducing SDS-PAGE.
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