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Rabbit Anti-SUSD2  antibody (bs-12850R)  
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產品編號 bs-12850R
英文名稱 Rabbit Anti-SUSD2  antibody
中文名稱 SUSD2蛋白抗體
別    名 1200011D11Rik; BK65A6.2; FLJ22778; SUSD2; SUSD2_HUMAN; Sushi domain-containing protein 2.  
研究領域 細胞生物  免疫學  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 88kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SUSD2: 301-400/822 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 SUSD2 (Sushi Domain Containing 2) is a Protein Coding gene. Diseases associated with SUSD2 include Breast Cancer. Gene Ontology (GO) annotations related to this gene include scavenger receptor activity and polysaccharide binding. An important paralog of this gene is MUC4.

Function:
May be a cytokine receptor for C10ORF99. May be a tumor suppressor; together with C10ORF99 has a growth inhibitory effect on colon cancer cells which includes G1 cell cycle arrest (PubMed:25351403). May play a role in breast tumorigenesis (PubMed:23131994).

Subcellular Location:
Membrane.

Tissue Specificity:
Highly expressed in breast cancer, but shows a restricted expression pattern in normal tissues such as adipose, adrenal gland, kidney, lung, mammary gland, placenta, thyroid, trachea, and uterus (PubMed:23131994). Also expressed in colon; down-regulated in colon cancer tisues (PubMed:25351403).

Similarity:
Contains 1 AMOP domain.
Contains 1 SMB (somatomedin-B) domain.
Contains 1 Sushi (CCP/SCR) domain.
Contains 1 VWFD domain.

SWISS:
Q9UGT4

Gene ID:
56241

Database links:

Entrez Gene: 56241 Human

SwissProt: Q9UGT4 Human

Unigene: 131819 Human



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