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Rabbit Anti-LINGO2  antibody (bs-18284R)  
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產品編號 bs-18284R
英文名稱 Rabbit Anti-LINGO2  antibody
中文名稱 富含亮氨酸重復跨膜神經元2抗體
別    名 LERN3; Leucine rich repeat and Ig domain containing 2; Leucine rich repeat neuronal 6C; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine-rich repeat neuronal protein 3; Leucine-rich repeat neuronal protein 6C; LIGO2_HUMAN; LINGO2; LRRN6C.  
研究領域 細胞生物  神經生物學  跨膜蛋白  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human (predicted: Mouse,Rat,Pig,Cow,Zebrafish,Chicken,Dog,Horse)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 65kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LINGO2: 331-430/606 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 ?Lingo-2 (leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2), also known as LERN3 (leucine-rich repeat neuronal protein 3) or LRRN6C, is a 606 amino acid single-pass type I membrane protein. Lingo-2 contains 1 immunoglobulin-like C2-type domain and 13 leucine-rich repeats. Lingo-2 is a member of the LRR gene family and has been linked to essential tremor and Parkinson’s disease. Lingo-2 has a high degree of homology (61%) with Lingo-1, a regulator of neuronal death, and the expression of Lingo-2 seems to be restricted to neuronal tissue.

Subcellular Location:
Membrane.

Similarity:
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 12 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

SWISS:
Q7L985

Gene ID:
158038

Database links:

Entrez Gene: 158038 Human

Entrez Gene: 242384 Mouse

Omim: 609793 Human

SwissProt: Q7L985 Human

SwissProt: Q3URE9 Mouse

Unigene: 726303 Human

Unigene: 745029 Human

Unigene: 132507 Mouse



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