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Mouse Anti-HBeAg  antibody (bsm-2022M)  
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說明書: 50ul  100ul  200ul
50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
200ug(PBS only)/5600.00元
大包裝/詢價

產品編號 bsm-2022M
英文名稱 Mouse Anti-HBeAg  antibody
中文名稱 人乙型肝炎e抗原單克隆(包被)抗體
別    名 External core antigen; Precore protein; p25; C; HBEAG_HBVD3;  
Specific References  (1)     |     bsm-2022M has been referenced in 1 publications.
[IF=4.996] Garg, Garima. et al. Presence of entry receptors and viral markers suggest a low level of placental replication of hepatitis B virus in a proportion of pregnant women infected with chronic hepatitis B. SCI REP-UK. 2022 Oct;12(1):1-11  IHC ;  Human.  
研究領域 免疫學  細菌及病毒  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 2E9
交叉反應 HBV
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 18kDa
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 HBeAg full length protein 
亞    型 IgG
純化方法 affinity purified by Protein G
緩 沖 液 0.01M PBS (pH7.4) with 0.02% Proclin300.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into “hiding,” the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.

Function:
May regulate immune response to the intracellular capsid in acting as a T-cell tolerogen, by having an immunoregulatory effect which prevents destruction of infected cells by cytotoxic T-cells. This immune regulation may predispose to chronicity during perinatal infections and prevent severe liver injury during adult infections.

Subunit:
Homodimerizes.

Subcellular Location:
Secreted. Host nucleus.

Post-translational modifications:
Phosphorylated.
Cleaved by host furin.

Similarity:
Belongs to the orthohepadnavirus precore antigen family.

SWISS:
P0C573

Gene ID:
N/A

Database links:

SwissProt: Q89714 Hepatitis B virus



產品圖片
Sample: Lane 1: Recombinant HBcAg protein, Tag free Lane 2: Recombinant hepatitis B virus e virus like particle protein, His Primary: Anti-HBeAg (bsm-2022M) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 18 kDa Observed band size: 25 kDa
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